New: NCI-funded clinical trial search
Mednet Logo

When treating an inoperable patient with squamous cell carcinoma of the thoracic esophagus, do you ever dose escalate beyond 50.4Gy?

What doses do you use?
1 Answer
Mednet Member
Mednet MemberInvited Expert
Radiation Oncology · University of Wisconsin Hospital & Clinics
Answered on

Given the results of INT-0123/RTOG9405 failed to demonstrate an improvement in overall survival with dose escalation, I do not treat above 50.4 Gy when giving definitive chemoradiation. There is no other randomized evidence to support doses greater than 50-50.4 Gy at 1.8-2.0 Gy/day.

Patients treated ...

Join for free or sign in to see the full answer