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When treating an inoperable patient with squamous cell carcinoma of the thoracic esophagus, do you ever dose escalate beyond 50.4Gy?

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Mednet Member
Radiation Oncology · University of Wisconsin Hospital & Clinics

Given the results of INT-0123/RTOG9405 failed to demonstrate an improvement in overall survival with dose escalation, I do not treat above 50.4 Gy when giving definitive chemoradiation. There is no other randomized evidence to support doses greater than 50-50.4 Gy at 1.8-2.0 Gy/day.

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