When would you consider larynx preservation in patients with T4N+ SCC of the larynx?

Most T4 patients should not undergo CRT alone. Surgery, followed by postoperative radiation, remains the standard of care for most patients with T4 disease. For patients who decline surgery, concurrent CRT is the best alternative and is superior to radiation alone. However, it is likely still inferi...

Yes, if the primary tumor volume was less than 4 cc and the larynx was functional.