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When would you include the superior mediastinal lymph nodes when treating head & neck cancer and how do you define the target volume?

Only when esophagus or thyroid involved? Or also when subglottis and hypopharynx involved? How do you define the CTV border? Some commonly stated boundaries: Superior: Suprasternal notch (AJCC; NCCN) Inferior: Innominate (NCCN H&N section) but carina (NCCN thyroid section) Anterior: Sternum (NCCN; AJCC) Posterior: Trachea/esophagus (NCCN; AJCC)
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When would you include the superior mediastinal lymph nodes when treating head & neck cancer? (select all that apply)

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2 Answers
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Radiation Oncology · University of Florida
Answered on

Low level 4 and/or 6 nodes.

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Mednet Member
Mednet Member
Radiation Oncology · Banner MD Anderson Cancer Center
Answered on

At our institution, we extend treatment volumes to the upper mediastinum in the following circumstances:

  • Level 4B node involvement (of any size)
  • Bulky nodal involvement of levels 4A or 4B
  • Level 6 nodal involvement
  • Thyroid primary

We do not treat the upper mediastinum routinely for subglottic exten...

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