Which patients will have earlier diagnosis of multiple sclerosis via the new 2024 McDonald Criteria?  

I think the group that will most benefit from the new diagnostic criteria, in terms of earlier diagnosis, is those with a history of optic neuritis. This is because the new criteria expand "typical CNS topographies" from four to 5 to include the optic nerve. In addition, those who present with lesio...

Patients who will have an earlier diagnosis of MS are those who were previously considered to have the radiologically isolated syndrome and patients who present with optic neuritis and have one other typical location (periventricular, juxtacortical, infratentorial, or spinal cord). The latter patien...