Where in your treatment approach to fibromyalgia will you recommend sublingual cyclobenzaprine? 

The choice of medication for any given patient is based on a lot of factors and, realistically, is often highly dependent on affordability and insurance coverage across different pharmacy plans. Despite other FDA-approved options, oral cyclobenzaprine is usually the medication I reach for first with...

When to integrate sublingual cyclobenzaprine will depend on the patient's circumstances. Many patients referred to a pain clinic may have already "failed" other agents. Take a good medication history first. What was the specific side effect, and try to understand if there was a mechanistic cause to ...

I would recommend that sublingual cyclobenzaprine be considered as a first-line agent in FM patients who have not received trials with other medications. I would use it as a single agent at night, similar to amitriptyline or cyclobenzaprine, especially in newly diagnosed patients. Initially, patient...