Which patients with intermediate and high risk prostate cancer should not receive androgen deprivation therapy?
More specifically, which cardiac risk factors do you look for? Diabetes? Previous MI? Dyslipidemia? Peripheral vascular disease? CHF?
Answer from: Radiation Oncologist at Academic Institution
Based on randomized trials that didn't exclude patients with cardiac risk factors, an overall survival benefit has been observed for intermediate and high risk localized prostate cancer. Review of RTOG studies has not detected an increase in cardiovascular events. That said, appropriate ...
Answer from: Radiation Oncologist at Academic Institution
For men with intermediate risk disease, the juryâs still out pending RTOG 0815 as to which men will benefit most from ADT. Retrospective data suggest that a âfavorableâ intermediate risk group can be identified, that behave similarly to low risk ...