Which tumor markers, if any, would you use to follow patients with high grade or advanced endometrial cancers?
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In which scenario(s) would you use tumor markers to monitor an endometrial cancer patient?
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2 Answers
Mednet MemberInvited Expert
Gynecologic Oncology · Sarasota Memorial Health Care System
Answered on
I typically check CA-125 in high-grade serous uterine cancer (and I think it’s reasonable to consider in any high-risk histology) pre-op (or pre-chemo or radiation if not operable). If elevated, I use it for surveillance. If not, I don’t. Of course, there is a questionable utility to using CA-125 fo...
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Mednet MemberInvited Expert
Gynecologic Oncology · Rutgers RWJ Medical School
Answered on
Elevated initial CA 125 has been associated with increasing tumor size, higher stage, poorer survival, and risk of recurrence in patients with high-grade uterine cancers. I do follow these women with serial testing throughout and after their initial treatment. Hoping that we will identify more speci...
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