Why are patients getting enzalutamide s/p prostatectomy not candidates for salvage radiation therapy?

Although there have been other efforts to profile the role of enzalutamide (e.g., SALV-ENZA, Tran et al., PMID 36367998) or other second generation androgen axis inhibitors (e.g., FORMULA-509) in conjunction with salvage RT, EMBARK (Freedland et al., PMID 38320501) was designed to test the efficacy ...

I’ve asked this question to people on the EMBARK trial as well as reps and presenters, since it came out.

I very rarely use EMBARK. The main problem was the lack of PET. The study quoted above for the "EMBARK-like" cohort at UCLA supports my practice pattern.

I will, however, discuss EMBARK with pati...