Why is pT3 not a PORT indication for glottic larynx in the NCCN guidelines?
pT3 glottic larynx is a somewhat unusual finding in typical clinical practice since modern imaging is quite good at detecting T3 lesions and most of these will be treated with definitive chemoradiotherapy. Downstaging from cT4 to pT3 would also be unusual because cT4 findings on imaging are fairly s...
A fixed cord high volume T3 likely has at least 1 cm of subglottic extension and should receive postop RT because of the risk of level 6 nodal mets. A low volume T3 fixed cord or mobile cord with para glottic space invasion (stage migration) should not have undergone total laryngectomy. However, if ...
Laryngectomy is an en bloc resection outside fascial planes. Widely negative margins are much more believable and represent a much lower risk of recurrence than in other subsites of the head and neck. In other areas, resection is often not even attempted for T3 lesions because lesions are usually T3...