Does oral Wegovy have a worse side effect profile compared to its injectable version?

From a clinical standpoint, I would say that oral semaglutide does cause more nausea and other GI side effects than injectable semaglutide for comparable doses. I am not aware of any randomized trials looking at this question, but there are single-center retrospective studies corroborating my impres...

To the best of my knowledge, a direct comparison of the side effects of the oral versus the injection has not been carried out. However, since the active ingredient of both forms of Wegovy is the same (Semaglutide), the side effects are expected to be similar. The most common side effects are nausea...