Would a longstanding diagnosis of multiple sclerosis impact your radiation recommendations for a patient with breast cancer?

In my opinion, the simple answer is no. At least not in my experience treating one MS patient with whole breast radiation. Unlike Scleroderma, which is an autoimmune disease that can result in inflammation and thickening of the skin, connective tissues, and internal organs, MS is an autoimmune disease that primarily targets the myelin sheath, leading to inflammation and damage to the nerves involving the brain and spinal cord. Hence, there are some concerns about the radiation of the central ner...