Would you add HER2 targeted therapy to adjuvant chemotherapy for a patient with initial breast biopsy showing a ER/PR positive, HER2 negative invasive ductal carcinoma but mastectomy sample showing equivocal Her2 by FISH on initial assay with an alternative probe testing positive?  

(HER2/CEP17 ratio <2.0, copy number >4.0 and <6.0 signals/cell)

Answer from: Medical Oncologist at Academic Institution