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Questions discussed in this category

Young healthy patient, ER/PR positive HER2 negative right breast cancer with a synchronous single site of oligometastatic disease in the right 4th rib...

What type of adjuvant chemotherapy would you offer? Would clinically positive lymph nodes or residual disease at the time of surgery change your decis...

If so, how many cycles would you give? Both the MAGIC and FLOT trials showed difficulty with administering adjuvant chemotherapy.

Would you consider definitive local therapy (surgery, radiation?) if she achieved a good response to initial systemic therapy?

Patient is young and reoccurrence is one year after initial diagnosis of T1cN0 ER/PR positive, HER2-negative breast cancer treated with mastectomy, bu...

Would you consider neoadjuvant or adjuvant treatment and if so, which therapies? Patient initially had pT2N0 disease and recurrent disease is also ER+...

Colleagues in surgery have raised concerns about post radiation effects in the pelvis with the ordering of short course RT->chemo ->surgery.

For example, will you recommend a certain vaccination timing in relationship to their treatment? Any concerns for reduced immune response or risks of ...

Does the advent of more effective therapies like peptide receptor radioligand therapy (PRRT) and capecitabine and temozolomide (CAPTEM) dampen enthusi...

She had had 4 prior biopsies. Would the fact that she received 2 months of neoadjuvant tamoxifen due to COVID change your approach?

This patient underwent mastectomy and ALND (10/28 positive lymph nodes). Immediately following axillary LN dissection (and prior to radiation) imaging...

For example, if you had a triple positive breast cancer found on breast biopsy and repeat ER/PR/HER2 testing at the time of surgical resection showed ...

In your experience, what approach has been successful to bridge to surgery?

Is this new SSO choosing widely guideline being widely adopted and are there any concerns regarding this for clinical practice?

In a patient treated over 10 years ago with mastectomy and chemo now with recurrence in the ipislateral axilla, would you offer additional with chemot...

Papers discussed in this category

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2018-04-10

J Clin Oncol, 2022 Apr 11

N Engl J Med, 2018 Oct 20

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013-07-01

Annals of surgical oncology, 2011-01

N. Engl. J. Med.,

JAMA Oncol,

J. Clin. Oncol., 2020 Feb 27

The New England journal of medicine, 2012-02-09

N. Engl. J. Med.,

Annals of surgery, 2019-04-05


J. Clin. Oncol., 2013 Aug 26

JAMA oncology, 2019-06-01

Lancet Oncol., 2020 Feb 14

Proceedings of the National Academy of Sciences of the United States of America, 2015-11-03

Oncologist, 2020 Mar 10

Semin Diagn Pathol, 2016 Dec 23

Lancet Oncol, 2020 Dec 07

Ann Oncol,

Lancet Oncol, 2021 Apr 13

Clinical cancer research : an official journal of the American Association for Cancer Research, 2018-12-01

JAMA Oncol, 2020 Aug 13

Annals of oncology : official journal of the European Society for Medical Oncology, 2000-08

The New England journal of medicine, 2017-01-12

Seminars in oncology, 2018-08

Endocrine-related cancer, 2016-09

Pancreas, 2017-07

JAMA Oncol, 2020 Apr 16

Pancreas, 2020 Jan

Surg Oncol Clin N Am, 2020 Oct 20

Scand J Gastroenterol, 2019 Aug 01

J Am Coll Surg, 2017 Jan 11

J Clin Oncol, 2018 Jun 07

Clin Cancer Res,

J. Clin. Oncol., 2020 Sep 20

Cancer, 2019 Jul 18

J Clin Oncol, 2021 Dec 10

The Lancet. Oncology, 2014-02

N Engl J Med, 2015 Jan 8

Front Oncol, 2018 Apr 17

The New England journal of medicine, 2018-07-12

N Engl J Med, 2021 Jun 03

J Clin Oncol, 2022 Jan 07


Ann Surg,

Annals of surgery, 2010-09

Journal of reconstructive microsurgery, 2022 Feb 14

Annals of surgery open : perspectives of surgical history, education, and clinical approaches, 2023 May 02