Would you add voclosporin to mycophenolate for refractory proteinuria in a patient with low EF?
1 Answer
Mednet MemberInvited Expert
Rheumatology · Uniformed Services University of the Health Sciences (USUHS)
Answered on
There are two major potential concerns in a lupus nephritis patient with systolic dysfunction and a left ventricular ejection fraction (LVEF) of only 30%:
- QTc prolongation potential worsening leading to acute cardiac death
- Exacerbation of hypertension leading to worse LVEF and CHF
However, with prop...
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