Would you alter your treatment algorithm for uterus mesonephric-like adenocarcinoma?

Very rare entity and would follow management principles for high grade (g3) endometrial cancer.

Would strongly recommend VCB regardless of other pathological factors for a mesonephric or mesonephric-like adenocarcinoma. We generally treat these similarly to type II (serous/clear cell/carcinosarcoma) endometrial cancers and recommend chemotherapy as well, especially if myoinvasive. No prospecti...

For IA grade 3 mesonephric adeno ca, I would consider vaginal cuff brachytherapy.