Would you avoid chemotherapy in a postmenopausal woman age >65 with T3 HR+/HER2 negative with Oncotype DX < 25?  

Prior to RxPONDER, we had to speculate: https://www.themednet.org/question/8265. We have more data now. RxPONDER included T3 patients (252 or 5% were T3) (Supplementary Appendix). So my answer mirrors that of the Oncotype website: "Postmenopausal women with 1 to 3 positive nodes and Recurrence ...