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Would you boost a positive margin (R1 resection or R2 resection) in a GEJ esophageal carcinoma that completed neoadjuvant chemoradiation?

What if the patient was not a candidate for additional chemotherapy? Would your answer change if the patient received the CROSS regimen with <50 Gy?
1 Answer
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Radiation Oncology · Memorial Sloan-Kettering Cancer Center
Answered on

Theoretically this might be feasible if it is a radial margin and not a mucosal margin because the irradiated mucosal structures would have been resected. There is no evidence-based answer to this question and I'm sure there are people that feel that further radiation is indicated. Not all patients ...

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