Would you consider a third course of radiation to the same site for late lung cancer in-field recurrence?

There are several important issues to consider before you even considering treating this patient

1. Are you sure it's a recurrence? If PET/CTs are used for follow up, false positives are very common. It is vital to ensure there is nodularity (more likely to be a recurrence). Offering a course of anti...

Here are my thoughts:

• Where the recurrence is relative to surrounding OARs is critical. For example(s):
  • A peripheral pulmonary nodule near the chest wall and lateral to the central structures, plexus, cord, etc with surrounding fibrosis from prior treatment is a much safer bet for re-re-treatment....