There is data on using other APBI techniques with preexisting implants, ex. interstitial brachytherapy.I have used Florence regimen on patients with implants but counseled they were not included in the study and warn about the risk of capsular contracture.

There is also data using TARGIT-IORT in patients with implant augmented breasts in order to avoid contracture. I offer this treatment option regularly.Kolberg et al., PMID 31366508