Would you consider applying the principles of STAMPEDE with <5 oligometastatic non-regional lymph nodes from prostate cancer?

About 25% in STAMPEDE had low volume metastatic disease with no bone Mets, with most having a non-regional node in that category to qualify as low volume Mets.

That being said, common iliac could be the primary drainage of prostate cancer based on SNLN studies and I would favor treating like node-pos...

There isn't "no mention" of non-regional nodal disease in STAMPEDE, nor does one have to extrapolate the principles.

From the paper directly: "Low metastatic burden disease is sometimes known as oligometastatic. Although this term is widely used, it is imprecise and potentially misleading because it ...

There was a subset analysis of STAMPEDE (Ali et al., PMID 33599706). They looked at refined definitions of metastases which looked at: bone Mets, visceral Mets, and non-regional nodal disease.

Prostate RT had no survival benefit with visceral Mets.
It appeared best with 3 or less bone Mets.
Non-regi...