Topics:
Breast Cancer • Medical Oncology
Would you consider doing Oncotype for a locoregional recurrence of ER positive breast cancer?
Can repeating Oncotype on a locoregional recurrence show a change in the biologic behavior of the cancer over time and guide treatment decisions?
Answer from: Medical Oncologist at Academic Institution
To re-phrase the question, would evidence that a local recurrence is biologically more aggressive than the primary affect our recommendations about administering adjuvant chemotherapy in a patient who recurred on adjuvant endocrine therapy, especially if she had never received adjuvant chemotherapy?...
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Answer from: Medical Oncologist at Community Practice
I wouldn't use RS in this instance unless I suspect a new primary. It might be useful to go back and understand why local failure occurred, how far out, treatment given in the past and what the patient is currently on, whether this seems to be a surgical issue or a disease biology issue,..etc. The r...
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Medical Oncologist at Lehigh Valley Physicians Group
How can differentiate LRR from new primary if both...
How can differentiate LRR from new primary if both...
Answer from: Medical Oncologist at Community Practice
Thank you. That was very helpful.
Answer from: Medical Oncologist at Community Practice
Can be difficult to differentiate a LR from a new primary. ER/PR/HER2, grade, location of new event, timeline, etc. Sometimes it is blurred, and reviewing course and pathology/radiology in Tumor Board would be helpful to put the story together.
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Medical Oncologist at R and B Lewis Cancer Care Center
Radiation therapy used to be given to entire breas...
Radiation therapy used to be given to entire breas...