Would you consider moderate hypofractionation for men with large prostate (>100cc) and poor AUA/IPSS score?

Size of the prostate, per se, is not a contraindication to moderate hypofractionation, if you can meet your dose constraints. However, I am much more concerned about a poor AUA/IPSS score when recommending radiation. I prefer conventional fractionation EBRT in these patients. In my experience, their...