Would you consider repeat lumpectomy and external beam partial breast reirradiation for in-breast recurrent cancers?

Patients experiencing a localized recurrence in a breast previously treated with lumpectomy and whole breast radiation are appropriately offered salvage mastectomy with or without reconstruction as an acceptable standard. However, many patients wish to have options that preserve the breast. Repeat l...

I offer this as a reasonable alternative to mastectomy to eligible and motivated breast cancer patients who have had an in-breast recurrence. At 5 years, ~ 95% of patient's enrolled on NRG RTOG 1014 had kept their breast and were free of a second local recurrence event. Patient's received appropriat...