Would you consider the addition of trabectedin to adjuvant doxorubicin in a patient with IVB leiomyosarcoma with completely resected disease (hysterectomy and thigh mass with negative margins)?

When do you include trabectedin in the first-line systemic treatment of patients with leiomyosarcoma?

• Only for patients with unresectable/residual disease
• For any patient for whom adjuvant chemotherapy will be recommended
• I do not include trabectedine in first-line chemotherapy treatment
• Other