Would you consider using adjuvant chemotherapy for a patient with anal squamous cell carcinoma with a positive surgical margin after APR done for persistent/progressive disease after chemoradiotherapy?
Answer from: Medical Oncologist at Academic Institution
There is no evidence that postoperative chemotherapy can alter the negative prognostic significance of a positive surgical margin after APR and improve long-term outcomes. Consequently, I would monitor this patient closely and initiate treatment only when warranted by clinical and/or radiographic pr...
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Medical Oncologist at SSM Cancer Care I posted a similar question recently.
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