Would you cover regional nodes in an early-stage breast cancer with a non-mapping sentinel lymph node?
Based on the SSO Choosing Wisely Guidelines (https://www.surgonc.org/wp-content/uploads/2020/11/SSO-5things-List_2020-Updates-11-2020.pdf) to not routinely use SLN biopsy in clinically node negative women ≥70 years of age with early stage hormone receptor positive, HER2 negative invasive breast canc...
I would include levels 1 and 2 in the RT field if the patient opts for whole breast RT.
I'd cover the SCV.
Known risk factors:
Grade 3 disease
Medial tumor location
High Oncotype score, declining recommended chemotherapy
Despite age > 70, given good health/life expectancy, other risk factors including LVSI or luminal B disease would lead me to cover regional nodes including the IM chain and SCV fossa. I ...
So we have a woman in her 70s with ER+ PR- HER2- stage 1a breast cancer who refuses chemotherapy and is considering RNI in addition to WBRT and endocrine therapy.
I don't believe one can show a survival advantage to RNI in this situation, although there was a meta-analysis done after PRIME II lookin...