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Would you ever consider pelvic exenteration followed by SBRT for a patient with recurrent cervical cancer (s/p chemoRT) who has disease only in the central pelvis and in a single hilar lymph node?

Certainly the distant disease makes the risk of recurrence after exenteration very high. On the other hand, the patient is 2 years out from initial treatment and disease seems to be slow-growing.
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Does the presence of any distant disease automatically render a patient ineligible for pelvic exenteration?

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2 Answers
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Gynecologic Oncology · The Ohio State University College of Medicine
Answered on

I think this is a tough question. The short of it would be that I would be very cautious with exent candidacy with extra-pelvic disease. The surgical morbidity and limited ability to get additional therapy are a reality. Scenarios where I might consider would be a long duration of time off therapy. ...

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Gynecologic Oncology · Washington University School of Medicine
Answered on

I would consider it.

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