Would you feel comfortable combining MMF and an IL-17 blocker in a patient with both limited scleroderma and psoriatic arthritis?
Answer from: at Academic Institution
We combine medications all the time! So the question is what is the risk-benefit? How bad psoriatic arthritis?
Otezla and orencia for scleroderma?
Otezla and MMF?
Why not IL-23? Vs IL-17?
Why not just methotrexate?
So many choices you have! Also, you can always start with both for 2-6months...
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Answer from: at Community Practice
Not so comfortable due to increased possibilities of immunodeficiency complications, neoplasias long term.