Would you give additional chemotherapy with taxane for a patient with triple negative breast cancer who has achieved pathologic complete response with Adriamycin and cyclophosphamide?

Topics: Breast Cancer • Medical Oncology

Answer from: Medical Oncologist at Community Practice

If there are no medical reasons to hold it and we believe the patient will tolerate it fairly well, I would give it. A large metanalysis presented at SABCS showed no difference in outcome between patients who received extra chemo or did not, after pCR. While these data give me comfort in omi...

Comments

Medical Oncologist
So if a large meta analysis indicates no need for ...

Medical Oncologist at NYU Winthrop Hospital
Thanks for this new treatment strategy.

Medical Oncologist at Clear Lake Specialties
What do you feel the rates of secondary leukemia a...

Answer from: Medical Oncologist at Academic Institution

The data from the PROGECT study using neoadjvuant carboplatin/docetaxel in TNBC suggests that they do well when they attain a pCR without giving an anthracycline. (Sharma CCR 2018) It is apparent that regardless of the preoperative regimen used, adjuvant chemotherapy will be...

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