theMednet - Would you give adjuvant chemotherapy to a premenopausal female who underwent bilateral mastectomies for ER+ pT2N1 disease, grade 1, with low oncotype (5)?

Topics: Breast Cancer • Medical Oncology • Breast Cancer, Non-metastatic

Would you give adjuvant chemotherapy to a premenopausal female who underwent bilateral mastectomies for ER+ pT2N1 disease, grade 1, with low oncotype (5)?

How would you approach management in setting of CHEK2 mutation?