Would you give PMRT for a radiation-induced G3 pleomorphic sarcoma measuring 5.4cm with closest margin to skin of 0.1cm, in the context of reconstruction and a VUS in TP53?

This is a really tough case, and I would be interested to hear what other sarcoma colleagues would do. Personally, I would not routinely recommend postoperative RT in this setting, but I would want more information before making a final recommendation. The high grade, 5.4-cm tumor and very close (1m...