Would you include any elective nodal stations for cases of T3/T4 node-negative NSCLC staged by PET/CT in which a patient cannot undergo nodal sampling?

In short, my answer is “no”. I do not target elective lymph nodes for NSCLC patients receiving definitive RT.

There are now a few RCTs for locally advanced NSCLC indicating that elective nodal irradiation can be omitted from concurrent chemoradiotherapy (Yuan et al [PMID 17551299], Nestle et al ...