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Would you offer adjuvant chemotherapy in a patient with extensive LCIS/DCIS s/p mastectomy and multiple positive lymph nodes due to surgical seeding?

If so, would you treat as node + BC with anthracycline and taxane regimen or non-anthracycline regimen (i.e docetaxel and cyclophosphamide)?
1 Answer
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Medical Oncology · Warren Alpert Medical School of Brown University
Answered on

I don't believe that multiple positive lymph nodes should be attributed to 'surgical seeding' alone, as opposed to invasive disease not visualized in the breast specimen (or apparent on preop imaging that included the axilla). Would ask my pathologist to perform receptors on the disease in the nodes...

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