Would you offer adjuvant radiation in addition to chemotherapy for a patient with stage IIIC uterine carcinosarcoma with cervical involvement?

This is a hard situation as there is no clear data for the exact treatment plan. For surgically staged patients with stage IIIC uterine cancer our tumor board treatment plans typically include discussion of PORTEC-3 (de Boer et al., PMID 31345626) and GOG-258 (Matei et al., PMID 31189035). Patients ...

My preferred approach is full-dose chemotherapy and vaginal brachytherapy.

Our institution recommends carbo/taxol instead of taxol/ifos. This is supported by the results of GOG 261 (ASCO 2019).

I would offer adjuvant radiation to this patient given the known risk of local recurrence based on uterine ...