Would you offer definitive RT to a patient with metastatic cervical adenocarcinoma s/p carbo/taxol/avastin with a partial response in the metastatic sites?

I have delivered definitive pelvic chemoradiotherapy to a handful of patients who had complete radiographic responses to neoadjuvant TCA. All patients remain disease-free several years later. As for a patient with only a partial response, I believe there is still a good argument to be made for the a...

I would not, with persistence metastatic disease in the lung. Palliative RT if needed.

I agree with both answers above. I too have given NACT for 3-6 cycles and had some patients with complete radiologic response to distant metastasis. These ladies then got definitive chemoradiation. Most remain disease free for a while with a handful never recurring. If however there is only a partia...