Topics:
Radiation Oncology • Gastrointestinal Cancers
Would you offer liver SBRT to a patient with a history of a liver transplant?
Assuming good liver function currently, without evidence for recurrent cirrhosis?
Would your decision be affected if it was a primary HCC vs Liver metastases (such as from colorectal cancer)?
Would the etiology of the need for liver transplant affect your decision (alcoholic vs NASH vs Hep B/C vs HCC)?
If you would offer treatment, would your proposed dose constraints differ from a non-transplanted liver?
Answer from: Radiation Oncologist at Academic Institution
At the University of Michigan, we have offered SBRT for patients who have failed intrahepatically post liver transplant with no metastatic disease. The risk of relapse of HCC post transplant is 15-20%. There is an interesting score developed by UCSF (RETREAT; Mehta et al., JAMA Onc 2016) in which th...
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