I have favored induction systemic therapy and interval re-assessment. If responsive or at least stable disease, I have offered extended field CRT as long as the treatment volume seems reasonable and my perception is that it would be tolerable when assessed in the context of a patient’s perform...

I agree with Dr. @Krishan R. Jethwa. We would typically start with 3-6 months of systemic therapy. This is less advanced disease than oligometastatic disease, and so I think it is appropriate to be aggressive. I haven't found that this particularly drives up toxicity, as that seems much more heavily...