Would you offer nodal RT for pT2N0 triple negative breast cancer s/p BCS?

I agree with above and generally haven't routinely offered RNI for such patients. However, I consider making an exception in the setting of a tumor with multiple risk factors, such as medial location, young age, large T2, poor response to neo-adjuvant chemotherapy (so cT2N0, ypT2N0) with LVI, etc.

In addition to what others have said, whole breast alone should be of strong consideration

However, the question of adding comprehensive regional nodal irradiation (C-RNI) for node negative (N0) patients is an intriguing one. Both MA.20 and EORTC 22922/10925 had a subset of patients who were N0. Both...

In my opinion, 2 separate answers are needed.

For high tangents, I absolutely offer hypofractionation to all patients regardless of receptor status, age, etc.

For regional nodal irradiation, my typical approach depends on surgery. If mastectomy with reconstruction,I offer the patient the alliance tr...