Would you offer PA nodal XRT in a patient with rising PSA and multiple PET positive nodes after previous prostate XRT treatment that is otherwise locally controlled?

This is a great question, and one that is being explored more and more, particularly for young, healthy patients with well-controlled primary disease. In addition, we are seeing more of these patients due to novel developments in imaging that can detect disease at much lower PSA values than before (...

https://www.ncbi.nlm.nih.gov/pubmed/31331782

The above study with the obvious limitation of retrospective analysis, suggests better regional nodal control with elective RT vs SABR for isolated nodal relapse detected on advance PET imaging and also better MFS in pts with single nodal disease.

Elective...