Would you offer preoperative radiation therapy when treating retroperitoneal sarcomas?

STRASS is a landmark trial and the authors deserve warm congratulations for completing a study of this scale in a rare disease. Its results are very important, but they also must be analyzed thoughtfully and taken in context.

Several initial points:

1. The primary endpoint was abdominal recurrence-free ...

Absolutely.

Thank you @Dr. First Last for pointing out the local control benefit shown in this trial and previous reports. Certainly, the treatment of patients with RPS needs to be individualized but when I make the assessment that preoperative radiation will have low morbidity in a certain case I tend to favor...