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Would you offer radiation to an elderly patient with cT2N1 triple negative breast cancer, whose lumpectomy and ALND showed a complete response to neoadjuvant chemotherapy?

Is the competing risk of a distant recurrence too high to justify doing radiation?
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Would you offer this patient adjuvant radiation?

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2 Answers
Mednet Member
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Radiation Oncology · Abramson Cancer Center, University of Pennsylvania
Answered on · Updated on

Yes, would offer.

This question is to be answered on NSABP B51, in regards to how to manage the axilla in patients who have a complete response in the nodes. All patients with intact breast receive at least breast RT. The primary endpoint is if breast/chest management with or without RNI will reduce...

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Mednet Member
Mednet Member
Radiation Oncology · Weatherby Health Care
Answered on

Patients older than 70 years with an estrogen receptor-positive cancer can be spared RT after BCS as studies have not shown an overall survival benefit. This patient, however, does not meet that criteria. She was offered and appropriately given aggressive curative therapy. As such, I don't believe i...

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