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Would you offer radiotherapy or chemotherapy a patient with cervical cancer s/p radical hysterectomy and now a delayed metastasis to the ovary that was completely resected without tumor spill?

The initial treatment did not include any adjuvant chemotherapy or radiation therapy.
2 Answers
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Radiation Oncology · University of Texas MD Anderson Cancer Center
Answered on

I agree with everything said so far. Extremely rare situation. I suppose I would add that the devil is sometimes in the details. Age? How far out from hysterectomy? was the ovary large? Difficult dissection that might suggest disease left in adjacent tissues? Also important to check with the pathologist that this could not be a second primary and even get second opinion if there is any uncertainty.

The prognosis is not great if it is a met but we have seen some cures even of patients with up front mets. I would discuss the utter lack of data with the patient. If the interval is not very long and she is motivated, I would be tempted to treat the pelvis and probably would give adjuvant carbo/taxol, particularly if it was a high grade tumor. ...

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Mednet MemberInvited Expert
Radiation Oncology · Varian Medical Systems/Allegheny health network
Answered on

Very limited data and no defined way to manage them.

We have treated few patients with concurrent pelvic RT with rationale that pelvic only relapse so potentially curable and not necessarily metastatic followed by pseudo adjuvant chemo with taxol and carbo

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