Would you offer re-irradiation for a prostate local recurrence after I-125 seed implant 14 years ago in a healthy young patient in his sixties?  

As advanced imaging has helped us better identify patients with local-only disease recurrence, the question of local therapies after prior radiation looms larger. ASCO GU 2024 had an excellent panel discussing surgical, focal, and radiation options for recurrences. Minor self-promotion, but I also t...

While I think salvage re-irradiation does have potential to become a routine option in such situations, I think further study is required to define both the efficacy and toxicity profile prior to establishing it as such. The current state of knowledge is based on limited information, as Dr. Janopau...