Would you offer SRS to a hippocampal metastasis in a patient with ES-SCLC treated with prior WBRT?

Would your dose or approach differ if the patient had had prior WBRT, HA-WBRT or not?

2 Answers

Mednet MemberInvited Expert

Radiation Oncology · University of Rochester

Answered on

I agree with Dr. @Dr. First Last. The brain metastasis is a greater risk to the patient than SRS would be. Whether the prior WBRT used hippocampal sparing or not would not change my recommendation.

I am not well-versed in neurocognitive anatomy. But it is feasible to injure (or remove) 1 hippocampus ...

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Mednet Member

Radiation Oncology · Maisonneuve-Rosemont Hospital

Answered on

Yes.

Consider adding memantine to reduce cognitive decline.

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