Would you omit a boost in a patient with an indication if a very large (>200cc) post-op seroma obscures the actual tumor bed?

Generally for these patients with seroma > 100 cc, prefer aspiration and settling of seroma before starting RT. Also in general, we tend to rescan for boost most of the time as favor lateral decubitus position and also account for change in size of seroma.
Kannan et al., PMID 23006598