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Would you omit IMN coverage in cN1 TNBC with a CR after neoadjuvant chemo?

While we are waiting for results from B51, could we omit internal mammary radiation in triple negative, cT1N1 breast cancet pts who have a complete pathologic response both in the breast and the axilla after neoadjuvant chemotherapy and breast conservation surgery?
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Would you cover IMNs for a patient with cN1 breast cancer who achieved a CR after neoadjuvant chemo?

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1 Answer
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Radiation Oncology · Allegheny Health Network, Pittsburgh
Answered on

My practice has been to offer RNI in patients with cN1 disease with pCR in axilla outside of a trial.

For TNBC in this situation, I would absolutely include IMNs in my RNI fields.

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