Would you recommend adjuvant chemotherapy for a patient who achieved a CR after TNT for stage III rectal adenocarcinoma but underwent no initial surgery, and now has a local recurrence >12 months later with plans to undergo low-anterior resection?
Total neoadjuvant therapy (TNT) included FOLFOX x 4 months and concurrent chemo-RT
Would you consider assessing circulating tumor DNA...
Is there really adjuvant therapy or second line th...
That may be helpful - if positive, you offer chemo...
Agree, these are challenging situations. My practi...