Would you recommend adjuvant chemotherapy for a patient who achieved a CR after TNT for stage III rectal adenocarcinoma but underwent no initial surgery, and now has a local recurrence >12 months later with plans to undergo low-anterior resection?  

Total neoadjuvant therapy (TNT) included FOLFOX x 4 months and concurrent chemo-RT



Answer from: Medical Oncologist at Academic Institution
Comments
Medical Oncologist at Edward-Elmhurst Health
Would you consider assessing circulating tumor DNA...
Medical Oncologist at Joliet Oncology - Hematology Associates, Ltd.
Is there really adjuvant therapy or second line th...
Medical Oncologist at University of Wisconsin
That may be helpful - if positive, you offer chemo...
Medical Oncologist at University of Virginia
Agree, these are challenging situations. My practi...
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