Would you recommend adjuvant therapy for a non-invasive Grade 3 endometrioid endometrial cancer that is P53 wild-type and MMR deficient (due to methylation)?

Topics: Gynecologic Cancers • Endometrial Cancer

Answer from: at Academic Institution

I would not give adjuvant therapy. The risk of nodal met is low based on GOG 33 and all other known data. Given that the tumor is p53 negative, I am going to assume it will not behave as a serous tumor.So, would observe.

Comments

at Methodist Stone Oak Hospital
I agree.

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