Would you recommend definitive XRT for prostate cancer in patients with prior Holmium Laser Enucleation of the Prostate (HoLEP)?

There are multiple options for outlet procedures in patients who present with baseline obstructive symptoms but prefer to avoid a radical prostatectomy. HoLEP is an effective procedure preferred by some urologists due to low re-treatment rates. HoLEP can often be quite aggressive leading to marked r...

HOLeP is not a cancer treatment, so prostate cancer patients still require definitive XRT.

In terms of fractionation scheme, limited data in this scenario: Laughlin et al., PMID 35790091.

Of 18 Mayo clinic patients, most got conventional, while 3 got mod hypofx and 1 got SBRT.

Institutionally, we wait ...